Paleo-Exercise

A report on an article in Journal of Physiology. (To see the original article: Booth, J. Phys 543(2) 399 (2002)

 

Much has been written about the "caveman," or "Pale­olithic," diet. The basic theory behind it is that while many changes have occurred in human society over the course of thousands of years, the human body remains the same as it was during the Stone Age. According to proponents of Paleolithic nutrition, most degenerative diseases com­mon today, such as cardiovascular disease, cancer and diabetes, result from the introduction of foods incompatible with human genetics. A less publicized aspect of the Paleolithic concept is how exercise enters the picture. A recent review discussed the relationship between human genetics and exercise.1

One relevant point is that ancient man and woman were far more active than modern people. Those who lived in the Paleolithic era not only burned far more calories than we do today, but by necessity they also had to do things like move heavy loads, which they alter­nated with getting sufficient rest so they could tackle an­other day of hard physical labor. The average ancient human had a physique that was on the muscular side. The activity level made the occurrence of obesity extremely unlikely. The problem today is that all humans still harbor genes that interact with intense physical activity. Paleolithic experts contend that the humans today who most resemble their Paleolithic forbears are champion athletes. Since the body is designed for activity, bad things happen when it doesn't get it regularly.

Studies examining hunter-gatherer societies that exist today, the so-called primitive peoples living in places such as Africa and New Guinea, show that cardiovascular disease, obesity and diabetes simply don't exist there. Yet when those people do move into a more modern society, they, too, become prone to the same degenerative diseases.

Sensible weight training provides many of the benefits of a Paleolithic lifestyle. Bodybuilding interacts with genetic factors that prevent dis­eases. Examples include the upregulation of glucose use in the body by exercised muscle, which prevents type II diabetes. Another exam­ple is the continued promotion of hormonal activity that would otherwise decline with age, such as the maintenance of insulinlike growth factor 1 (IGF-1), which helps to preserve both muscle and connective tissue.

A loss of muscle with age or disease is now considered a harbinger of impending death. It's called sarcopenia, and when sufficient muscle is lost, death is not far off. Most people who live in nursing homes are there because they have become so weak from loss of muscle that they can no longer care for themselves. Doctors know that when cancer or AIDS patients lose lean tissue mass, they often spiral into death. Keeping muscle keeps people alive.

Cardiovascular disease is a modern disease that results from a combination of dietary and lack-of­ exercise factors. The human heart has-or should have-a function predicated of an active lifestyle. Exercising regular­ly produces beneficial changes that favor cardiovascular fitness, such as increased production of nitric oxide, a chemical that dilates blood vessels, preventing high blood pressure and relieving some of the work of the heart. Hearts that aren't exercised inevitably fail. The point is that exercise is a mandatory part of human existence. Not exercising is a definite hazard to human health, resulting in a host of degenerative, life-shortening diseases. Perhaps the most interesting aspect of this is that the human body is geared for intense, regular exercise. It seems that a program that includes judicious doses of both weight training and aerobics is written in our genes.

 

1. Booth, FW., et  al. (2002). Exercise and gene expres­sion: physiological regulation of the human genome through physical activity. J Physiol. 543:399-41